Scaling of Traction Forces with Size of Cohesive Cell Colonies
نویسندگان
چکیده
Aaron F. Mertz, Shiladitya Banerjee, Yonglu Che, 1 Guy K. German, Ye Xu (??), Callen Hyland, M. Cristina Marchetti, 5 Valerie Horsley, and Eric R. Dufresne 6, 1, 7, ∗ Department of Physics, Yale University, New Haven, Connecticut 06520, USA Department of Physics, Syracuse University, Syracuse, New York 13244, USA Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, USA Department of Mechanical Engineering & Materials Science, Yale University, New Haven, Connecticut 06520, USA Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York 13244, USA Department of Chemical & Environmental Engineering, Yale University, New Haven, Connecticut 06520, USA Department of Cell Biology, Yale University, New Haven, Connecticut 06520, USA (Dated: March 21, 2012)
منابع مشابه
Scaling of traction forces with the size of cohesive cell colonies.
To understand how the mechanical properties of tissues emerge from interactions of multiple cells, we measure traction stresses of cohesive colonies of 1-27 cells adherent to soft substrates. We find that traction stresses are generally localized at the periphery of the colony and the total traction force scales with the colony radius. For large colony sizes, the scaling appears to approach lin...
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Submitted for the MAR12 Meeting of The American Physical Society Scaling of Traction Stresses with Size of Cohesive Cell Colonies1 AARON F. MERTZ, Yale University, SHILADITYA BANERJEE, Syracuse University, YONGLU CHE, Yale University, M. CHRISTINA MARCHETTI, Syracuse University, VALERIE HORSLEY, ERIC R. DUFRESNE, Yale University — We explore the mechanical properties of colonies of cohesive cel...
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